What is a potential outcome of overt GI injury?

A potential outcome of overt gastrointestinal (GI) injury is pathogenic overgrowth. When the integrity of the GI tract is compromised, whether due to an injury, infection, or other factors, the normal balance of gut microbiota can be disrupted. This disruption may allow harmful bacteria to flourish, leading to conditions such as dysbiosis. In such situations, the protective mechanisms of the gut are impaired, making it easier for pathogenic organisms to colonize and proliferate, which can cause further damage and exacerbate symptoms.

Pathogenic overgrowth can lead to a variety of digestive issues, increased permeability of the gut lining, and may also contribute to systemic inflammation. Understanding this relationship is critical for addressing complications that arise from overt GI injuries and is a key concept in maintaining gut health.